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Model output · Signal date Oct. 15, 2026

Daily SignalsNeutral

2696 companies scored · 2026-10-15 run in progress: 5121 of ~5380 signals so far · Alpha · vs marketSwitch to Total · 30D 90D

Signal date 2026-10-15 Cut-offs from the 2026-10-15 run
Companies scored 2696 IC ≥ 0 · market cap ≥ $100M
Median forecast -0.28% Alpha · 90D
Long–short spread +5.13% Strong Buy minus Strong Sell, mean
Median IC 0.28 Spearman · 90D
Rating changes ▲ 546 ▼ 698 vs the previous run
Cross-section

Distribution of the day's forecasts

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Signals · Neutral

63 companies

Sorted by 90D forecast ↓

# Ticker Sector IC Mkt cap Rating 30D 90D Δ
1 CYPHCYPHERPUNK TECHNOLOGIES INC. Life Sciences 0.17 $282M Neutral +0.11% +0.24% ·
2 PGENPRECIGEN, INC. Life Sciences 0.31 $2.6B Neutral +0.11% +0.24% ▼ 2
3 MISTMilestone Pharmaceuticals Inc. Life Sciences 0.07 $112M Neutral +0.10% +0.22% ▼ 1
4 HALOHALOZYME THERAPEUTICS, INC. Life Sciences 0.30 $13.3B Neutral +0.09% +0.21% ▼ 1
5 ANABANAPTYSBIO, INC Life Sciences 0.27 $1.5B Neutral +0.08% +0.19% ·
6 AMRNAMARIN CORP PLC\UK Life Sciences 0.05 $243M Neutral +0.07% +0.17% ·
7 GMABGENMAB A/S Life Sciences 0.02 $23.7B Neutral +0.07% +0.17% ·
8 ACBAURORA CANNABIS INC Life Sciences 0.17 $260M Neutral +0.07% +0.16% ·
9 SIGASIGA TECHNOLOGIES INC Life Sciences 0.47 $223M Neutral +0.23% +0.16% ·
10 MOLNMOLECULAR PARTNERS AG Life Sciences 0.04 $147M Neutral -0.10% +0.14% ·
11 ALNYALNYLAM PHARMACEUTICALS, INC. Life Sciences 0.57 $31.3B Neutral +0.05% +0.12% ▲ 1
12 SMMTSummit Therapeutics Inc. Life Sciences 0.31 $12.1B Neutral +0.04% +0.11% ·
13 HCMHUTCHMED (China) Ltd Life Sciences 0.12 $2.4B Neutral +0.04% +0.10% ·
14 KROSKeros Therapeutics, Inc. Life Sciences 0.15 $219M Neutral +0.04% +0.10% ▼ 2
15 LXRXLEXICON PHARMACEUTICALS, INC. Life Sciences 0.43 $712M Neutral +0.02% +0.07% ▼ 1
16 SPRYARS Pharmaceuticals, Inc. Life Sciences 0.25 $391M Neutral +0.99% +0.06% ·
17 ENGNenGene Therapeutics Inc. Life Sciences 0.32 $105M Neutral 0.00% +0.04% ▼ 2
18 INSMINSMED Inc Life Sciences 0.42 $21.4B Neutral 0.00% +0.03% ·
19 SABSSAB Biotherapeutics, Inc. Life Sciences 0.14 $227M Neutral -0.01% +0.02% ·
20 RGENREPLIGEN CORP Life Sciences 0.62 $10.1B Neutral -0.01% +0.01% ▼ 1
21 BBIOBridgeBio Pharma, Inc. Life Sciences 0.07 $13.1B Neutral -0.04% -0.04% ·
22 CLLSCellectis S.A. Life Sciences 0.13 $112M Neutral +1.29% -0.04% ·
23 XTLBXTL BIOPHARMACEUTICALS LTD Life Sciences 0.14 $1.9B Neutral +0.23% -0.05% new
24 QGENQIAGEN N.V. Life Sciences 0.17 $9.9B Neutral -0.05% -0.07% ▲ 1
25 AGIOAGIOS PHARMACEUTICALS, INC. Life Sciences 0.15 $1.9B Neutral -0.07% -0.10% ·
26 BHCBausch Health Companies Inc. Life Sciences 0.49 $2.4B Neutral -0.07% -0.10% ·
27 VTRSViatris Inc Life Sciences 0.36 $20.0B Neutral -0.09% -0.13% ·
28 AUTLAutolus Therapeutics plc Life Sciences 0.32 $458M Neutral -0.09% -0.14% ▼ 2
29 COGTCogent Biosciences, Inc. Life Sciences 0.21 $4.9B Neutral -0.09% -0.14% ▲ 1
30 CYRXCryoport, Inc. Life Sciences 0.30 $843M Neutral -0.10% -0.16% ▼ 1
31 NRIXNurix Therapeutics, Inc. Life Sciences 0.26 $2.5B Neutral -0.11% -0.18% ·
32 MRKMerck & Co., Inc. Life Sciences 0.21 $363.6B Neutral -0.11% -0.19% ▲ 1
33 CGENCOMPUGEN LTD Life Sciences 0.42 $189M Neutral -0.10% -0.22% ·
34 FTHFaeth Therapeutics, Inc. Life Sciences 0.06 $517M Neutral -0.14% -0.24% ▼ 2
35 GALTGALECTIN THERAPEUTICS INC Life Sciences 0.07 $367M Neutral +0.22% -0.26% ·
36 RIGLRIGEL PHARMACEUTICALS INC Life Sciences 0.06 $875M Neutral -0.15% -0.26% ▼ 2
37 NWBONORTHWEST BIOTHERAPEUTICS INC Life Sciences 0.00 $270M Neutral -0.07% -0.32% ·
38 INVAInnoviva, Inc. Life Sciences 0.07 $1.5B Neutral -0.22% -0.41% ▲ 1
39 BMRNBIOMARIN PHARMACEUTICAL INC Life Sciences 0.32 $10.8B Neutral -0.25% -0.47% ▲ 1
40 ABBVAbbVie Inc. Life Sciences 0.01 $500.7B Neutral -0.25% -0.48% ▲ 2
41 LLYELI LILLY & Co Life Sciences 0.23 $1.1T Neutral -0.25% -0.48% ▼ 1
42 PCRXPacira BioSciences, Inc. Life Sciences 0.25 $1.5B Neutral -0.26% -0.51% ·
43 KRYSKrystal Biotech, Inc. Life Sciences 0.18 $9.8B Neutral -0.28% -0.54% ▼ 1
44 ARDXARDELYX, INC. Life Sciences 0.38 $815M Neutral -0.28% -0.55% ▼ 2
45 LEGNLegend Biotech Corp Life Sciences 0.02 $3.5B Neutral -0.28% -0.55% ·
46 LKFTLakefront Biotherapeutics NV Life Sciences 0.39 $1.9B Neutral -0.28% -0.55% ▲ 1
47 REGNREGENERON PHARMACEUTICALS, INC. Life Sciences 0.23 $80.5B Neutral -0.29% -0.57% ·
48 DBVTDBV Technologies S.A. Life Sciences 0.36 $525M Neutral -0.31% -0.62% ▲ 1
49 AMPHAmphastar Pharmaceuticals, Inc. Life Sciences 0.40 $1.1B Neutral -0.31% -0.63% ·
50 BMYBRISTOL MYERS SQUIBB CO Life Sciences 0.43 $123.7B Neutral -0.32% -0.63% ▲ 2
1–50 of 63 Previous Next
Since the previous run

Rating changes

▲ 546▼ 698
Which companies were upgraded or downgraded is part of the paid plans.
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Methodology

Ratings are relative: the forecasts of the latest complete daily run (2026-10-15) are ranked and cut at the 15th, 35th, 65th and 85th percentiles, so Strong Sell is the bottom 15%, Sell the next 20%, Neutral the middle 30%, Buy the next 20% and Strong Buy the top 15%. Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. IC is the company's Spearman information coefficient between its past forecasts and the realised returns at the selected horizon; IC-weighted ranking multiplies each forecast by its IC (negative IC counts as zero). Δ is the rating move since the company's previous signal, in rating steps. Each company shows its latest signal, including one from a run still in progress; every signal is rated against the cut-offs above. Quantitative research output, not investment advice.