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Stock comparison · Signal date 2026-11-06

SLN vs SPTX: stock comparison and AI forecast

Silence Therapeutics Plc (SLN) and Seaport Therapeutics, Inc. (SPTX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

SLN Silence Therapeutics Plc

Price
$19.72 +167.9% · 6M
Market Cap
$1.19B
P/E Ratio
–
Size
small-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

SPTX Seaport Therapeutics, Inc.

Price
$20.39 +25.9% · 6M
Market Cap
$1.09B
P/E Ratio
–
Size
small-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-06-08 → 2026-11-05

Six-month price performance

Closing prices rebased to 100 at the start of the window.

90135180225270
SLN +167.9% SPTX +25.9%
SLN · SPTX

Key facts

  • SLN and SPTX have similar market capitalizations ($1.19B and $1.09B).
  • Over the last six months SLN returned +167.9% and SPTX +25.9%.
  • SLN carries 1.77 times debt per unit of equity, against 0.05 times for SPTX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricSLNSPTX
Market Cap$1.19B$1.09B
P/B Ratio30.93x2.75x
EPS$-0.53–
Book Value/Share$0.64$7.42
Revenue/Share$0.01–
FCF/Share$-0.70–

Profitability & Margins

MetricSLNSPTX
ROIC-72.9%–
Gross Margin69.8%–
Operating Margin-9023.4%–
EBT Margin-7919.6%–
Tax Rate0.0%–

Financial Health

MetricSLNSPTX
Current Ratio7.42x17.48x
D/E Ratio1.77x0.05x
Financial Leverage2.77x1.05x
Working Capital$82M$282M

Cash Flow

MetricSLNSPTX
Operating Cash Flow-$42M–
Free Cash Flow-$42M–
Capital Spending$0.00M–
FCF/Sales-5583.4%–
CapEx/Sales0.4%–

Operational Efficiency

MetricSLNSPTX
Asset Turnover0.01x–
Fixed Assets Turnover0.6x–

Income Statement

MetricSLNSPTX
Total Revenue$760K–
Operating Income-$68M–
R&D Expense$48M–
Cost of Goods Sold$90K–

Dividend & Shareholder Information

MetricSLNSPTX
Shares Outstanding60M54M
FAQ

SLN vs SPTX: stock comparison and AI forecast

Which is bigger, SLN or SPTX?

SLN and SPTX have similar market capitalizations ($1.19B and $1.09B).

Which stock performed better over the last six months, SLN or SPTX?

Over the last six months SLN returned +167.9% and SPTX +25.9%.

Which one does Intratio's AI model rank higher, SLN or SPTX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.