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Stock comparison · Signal date 2026-11-06

PTGX vs SMMT: stock comparison and AI forecast

Protagonist Therapeutics, Inc (PTGX) and Summit Therapeutics Inc. (SMMT) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Market Cap
$8.75B
P/E Ratio
171.2x
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

SMMT Summit Therapeutics Inc.

Market Cap
$11.32B
P/E Ratio
–
Size
large-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

PTGX · SMMT

Key facts

  • SMMT is 1.3 times larger than PTGX by market capitalization ($11.32B against $8.75B).
  • SMMT carries 0.23 times debt per unit of equity, against 0.05 times for PTGX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricPTGXSMMT
Market Cap$8.75B$11.32B
P/E Ratio171.21x–
P/B Ratio10.40x20.05x
EPS$0.79$-1.39
Book Value/Share$13.01$0.71
Revenue/Share$3.49–
FCF/Share$2.02$-0.66

Profitability & Margins

MetricPTGXSMMT
ROE–-147.5%
ROA–-120.2%
ROIC6.9%–
Operating Margin25.9%–
EBT Margin36.4%–
Tax Rate1.7%–

Financial Health

MetricPTGXSMMT
Current Ratio21.71x5.99x
D/E Ratio0.05x0.23x
Financial Leverage1.05x1.23x
Interest Coverage–-508.6x
Working Capital$770M$550M

Cash Flow

MetricPTGXSMMT
Operating Cash Flow$131M-$525M
Free Cash Flow$131M-$527M
Capital Spending-$610K-$2M
OCF Growth YoY231.8%–
FCF Growth YoY252.0%–
FCF/Sales57.9%–
CapEx/Sales0.3%–

Operational Efficiency

MetricPTGXSMMT
Asset Turnover0.25x–
Fixed Assets Turnover65.3x–

Income Statement

MetricPTGXSMMT
Total Revenue$226M–
Operating Income$58M–
Net Income–-$833M
R&D Expense$175M$607M

Dividend & Shareholder Information

MetricPTGXSMMT
Shares Outstanding65M798M
EPS Growth-14.1%–
FAQ

PTGX vs SMMT: stock comparison and AI forecast

Which is bigger, PTGX or SMMT?

SMMT is 1.3 times larger than PTGX by market capitalization ($11.32B against $8.75B).

Which one does Intratio's AI model rank higher, PTGX or SMMT?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.