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Stock comparison · Signal date 2026-11-06

IONS vs MIRM: stock comparison and AI forecast

Ionis Pharmaceuticals Inc (IONS) and Mirum Pharmaceuticals, Inc. (MIRM) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

IONS Ionis Pharmaceuticals Inc

Price
$38.80 -49.0% · 6M
Market Cap
$6.45B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

MIRM Mirum Pharmaceuticals, Inc.

Price
$96.97 -11.9% · 6M
Market Cap
$6.07B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-07 → 2026-11-05

Six-month price performance

Closing prices rebased to 100 at the start of the window.

607590105120
IONS -49.0% MIRM -11.9%
IONS · MIRM

Key facts

  • IONS and MIRM have similar market capitalizations ($6.45B and $6.07B).
  • Over the last six months MIRM returned -11.9% and IONS -49.0%.
  • MIRM turns -134.8% of its revenue into net income, against -213.0% for IONS.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricIONSMIRM
Market Cap$6.45B$6.07B
P/B Ratio14.66x–
EPS$-3.77$-15.88
Book Value/Share$2.65–
Revenue/Share$1.60$10.33
FCF/Share$-3.37$-4.22

Profitability & Margins

MetricIONSMIRM
ROE-128.5%–
ROA-18.9%-88.0%
ROIC-22.2%-120.5%
Gross Margin94.0%–
Operating Margin-224.0%-133.6%
Net Margin-213.0%-134.8%
EBT Margin-211.8%-134.2%
Tax Rate-0.6%-0.4%

Financial Health

MetricIONSMIRM
Current Ratio7.89x2.07x
Quick Ratio7.73x1.98x
D/E Ratio5.81x–
Financial Leverage6.81x–
Interest Coverage-22.1x-37.2x
Working Capital$2.18B$304M

Cash Flow

MetricIONSMIRM
Operating Cash Flow-$496M-$271M
Free Cash Flow-$561M-$274M
Capital Spending-$64M-$3M
OCF Growth YoY–-707.0%
FCF Growth YoY–-717.9%
FCF/Sales-211.4%-40.8%
CapEx/Sales24.3%0.4%

Operational Efficiency

MetricIONSMIRM
Asset Turnover0.09x0.65x
Receivables Turnover–4.3x
Inventory Turnover0.3x–
Fixed Assets Turnover1.7x206.3x
Days Sales Outstanding–85 days
Days Inventory1158 days–
Payables Period1087 days–

Income Statement

MetricIONSMIRM
Total Revenue$265M$671M
Operating Income-$594M-$896M
Net Income-$565M-$904M
R&D Expense–$347M
SG&A Expense$528M$341M
Cost of Goods Sold$16M–

Dividend & Shareholder Information

MetricIONSMIRM
Shares Outstanding166M65M
FAQ

IONS vs MIRM: stock comparison and AI forecast

Which is bigger, IONS or MIRM?

IONS and MIRM have similar market capitalizations ($6.45B and $6.07B).

Which stock performed better over the last six months, IONS or MIRM?

Over the last six months MIRM returned -11.9% and IONS -49.0%.

Which one does Intratio's AI model rank higher, IONS or MIRM?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.