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Stock comparison · Signal date 2026-11-06

ANNX vs COLL: stock comparison and AI forecast

Annexon, Inc. (ANNX) and Collegium Pharmaceutical, Inc (COLL) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

ANNX Annexon, Inc.

Price
$4.20 -23.9% · 6M
Market Cap
$796M
P/E Ratio
–
Size
small-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

COLL Collegium Pharmaceutical, Inc

Price
$25.16 -36.0% · 6M
Market Cap
$819M
P/E Ratio
16.9x
Size
small-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-07 → 2026-11-06

Six-month price performance

Closing prices rebased to 100 at the start of the window.

607590105
ANNX -23.9% COLL -36.0%
ANNX · COLL

Key facts

  • ANNX and COLL have similar market capitalizations ($796M and $819M).
  • Over the last six months ANNX returned -23.9% and COLL -36.0%.
  • COLL carries 6.07 times debt per unit of equity, against 0.31 times for ANNX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricANNXCOLL
Market Cap$796M$819M
P/E Ratio–16.88x
P/B Ratio3.76x2.76x
EPS$-1.28$1.49
Book Value/Share$1.12$9.11
Revenue/Share–$25.04
FCF/Share$-1.02$10.33

Profitability & Margins

MetricANNXCOLL
ROE-91.4%12.9%
ROA–1.8%
ROIC–8.3%
Gross Margin–59.0%
Operating Margin–15.2%
Net Margin–4.7%
EBT Margin–5.2%
Tax Rate–9.4%

Financial Health

MetricANNXCOLL
Current Ratio5.53x1.01x
Quick Ratio–0.87x
D/E Ratio0.31x6.07x
Financial Leverage–7.07x
Interest Coverage–1.1x
Working Capital$174M$9M

Cash Flow

MetricANNXCOLL
Operating Cash Flow-$193M$338M
Free Cash Flow-$193M$336M
Capital Spending-$180K-$2M
OCF Growth YoY–16.2%
FCF Growth YoY–16.2%
FCF/Sales–41.2%
CapEx/Sales–0.2%

Operational Efficiency

MetricANNXCOLL
Asset Turnover–0.39x
Receivables Turnover–2.6x
Inventory Turnover–3.8x
Fixed Assets Turnover–75.0x
Days Sales Outstanding–139 days
Days Inventory–96 days
Payables Period–11 days
Cash Conversion Cycle–224 days

Income Statement

MetricANNXCOLL
Total Revenue–$815M
Operating Income-$211M$124M
Net Income-$193M$38M
R&D Expense$175M–
SG&A Expense–$360M
Cost of Goods Sold–$334M

Dividend & Shareholder Information

MetricANNXCOLL
Shares Outstanding190M33M
Net Income Growth–-34.7%
EPS Growth–-22.0%
FAQ

ANNX vs COLL: stock comparison and AI forecast

Which is bigger, ANNX or COLL?

ANNX and COLL have similar market capitalizations ($796M and $819M).

Which stock performed better over the last six months, ANNX or COLL?

Over the last six months ANNX returned -23.9% and COLL -36.0%.

Which one does Intratio's AI model rank higher, ANNX or COLL?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.